During physical effort, our heart undergoes several hormonal stimulations which involve coronary vasoconstriction, a greater myocardial oxygen demand and a tachycardization. This method is used to assess cardiac ischemia and the patient’s  rhythmic profile.

67) Ivabradina in paziente con Cardiopatia cronica e test da sforzo positivo
G.Fazio, G.Di Gesaro, l.D’angelo, C.Visconti, P. Licata, S. Passantino, L.Sutera, G.Novo, S. Novo
Gestione della Cardiopatia Ischemica Stabile. Vol Unico. Centro Scientifico Editore

69) Wolff-Parkinson-White syndrome associated with Brugada syndrome.
Fazio G, Augugliaro S, Lunetta M, D’Angelo L, Visconti C, Di Gesaro G, Di Maio C, Novo G, Indovina G, Novo S.
Minerva Cardioangiol. 2009 Jun;57(3):361-4

75) Cardiopulmonary Exercise Testing in Patients with Chronic Heart Failure: Prognostic Comparison from Peak VO2 and VE/VCO2 Slope.
Sarullo FM, Fazio G, Brusca I, Fasullo S, Paterna S, Licata P, Novo G, Novo S, Di Pasquale P.
Open Cardiovasc Med J. 2010 May 26;4:127-34.

104) Impact of off label” use of ivabradine on exrcise capacity, gas exchange, functional class, quality of life, and neurohormonal modulation inpatients with ischemic chronic heart failure
Sarullo FM, Fazio G, Puccio D, Fasullo S, Paterna S, Novo S, Di Pasquale P.
J Cardiovasc Pharmacol Ther. 2010 Dec;15(4):349-55.. Epub 2010 Oct 12 (IF 4,200)